One question I constantly get asked by my clients is “what ONE gene is responsible for my health problem?”
It’s usually a combination of genes that, when looked at as a whole, predispose you to your health issues.
But, there are some genes that, on their own, have a huge impact on your health.
One of them is the COMT gene. This gene is one of the most important genes in genomics.
In fact, I would say that if you care about your health, it’s necessary to understand what COMT genetic variant you carry.
It is one of the most studied genes in genomics because of its huge effects on almost all of your bodily functions.
COMT helps break down many different types of neurotransmitters, like:
- Dopamine – the “happiness hormone” responsible for motivation, learning and memory, increased focus and more
- Norepinephrine – manages the body’s response to stress, important factor of the fight or flight response
- Epinephrine – high levels of epinephrine can cause a weak immune system and heart problems
- Estrogens – plays roles in sexual reproduction, brain health, cancer risk, and more.
So your COMT activity might be to blame for your mood issues (like anxiety, depression), your cognitive function (brain fog, lack of mental clarity), and even your risk of developing many different types of cancer.
Let’s take a look at one of the many ways the COMT gene drastically affects one aspect of your life.
When you find yourself in an extremely stressful, high pressure scenario, what is more likely to happen to you?
Are you going to start feeling overwhelmed, worried and unable to finish the task at hand? Or are you able to improve your focus, double down on your work and get it done more efficiently?
The difference in your reaction to the situation is based on your COMT activity, which is determined by your genetic variant. It has such a strong effect on your response that they actually call it the Worrier/Warrior gene!
Norepinephrine is a stress hormone that is released and helps prepare the brain for when stressful situations arise. However, sustained stimulation can cause anxiety.
With low COMT activity, norepinephrine neurotransmitter is broken down more slowly, so it’ll take you longer to adapt to stress. On the other hand, highly active COMT variants break down these neurotransmitters quickly, which helps recovery during periods of stress.
This fight or flight response is only one function norepinephrine is responsible for. There’s also “remember or forget” and “distraction or focus”, and your COMT activity is a determining factor in all of these.
You need to know if your COMT is low, moderate or high activity in order to understand your strengths and weaknesses as they relate to your health – and more importantly, how to balance your levels depending on what you’re predisposed to.
If there was a reliable and available COMT blood test, I would highly recommend people get it done. However, you can’t check for COMT levels in the brain with a blood test.
That’s where genetics comes in. With your genetic data, we can accurately tell you what your COMT levels are like in your brain.
If you had to get your genetics tested just for this gene and you wouldn’t find out any other information, it would be worth it (but you obviously get way more).
COMT helps break down many different neurotransmitters, and once you realize the number of body functions each neurotransmitter is responsible for, you’ll start to see how important the COMT gene is.
This is why we’ve just launched our brand new COMT DNA Report, and it is by far the most accurate COMT Report out there, because we know just how important it is.
The other COMT Reports that you find on the market just analyze one variant of one SNP of your COMT gene, and use that data to tell you what effects your COMT gene variant has on your health. But, that’s not how it actually works. There are multiple variants that you need to look at together to get an idea of what your COMT activity levels are like.
Our COMT DNA Report accurately measures your COMT activity in two ways:
- We analyze multiple SNPs of the COMT gene, look at your variants and use the combination of that data to get a way more accurate representation of your COMT activity.
- We also look at other genes that influence the effects of your COMT gene and analyze those relationships when determining your COMT activity levels.
After determining your overall COMT activity, you’ll get personalized diet, lifestyle, and supplement recommendations that completely optimize your COMT activity.
You’ll be able to determine your COMT levels and implement personalized recommendations that will help with your mood, cognitive function, heart health, sleep, cancer risk, and so much more.
Like always, with a SelfDecode membership, you’ll get access to all these amazing other features as well:
- Comprehensive DNA health reports on topics like cognitive function, mood, sleep, inflammation, weight loss and more!
- Access to ALL of your personalized results on the SelfDecode blog to check your genetic scorecards and see what you need to change to combat bad genes.
- Ability to track and analyze your lab test results to get diet, lifestyle and supplement recommendations that will help you get your levels in the optimal range.
- Unlimited AD-FREE access to SelfHacked.com, the world-renowned health information website