NOS3, PON1 & CNR1 Genes: Personalized Genetics Blog Roundup! Get In Your Partner’s Genes

Written by Joe Cohen, BS | Last updated:

I’ve been keeping busy with studying my NOS3, PON1 and CNR1 genes, and using the Personalized Genetics Blog to look at all the different areas of my health that these genes can affect.

We’ve had a ton of new articles going up recently and one thing that has become even more apparent to me is how having certain variants for a gene can affect different areas of your health in different ways. Depending on the topic, my scorecard for a gene can be completely opposite.

It’s actually fun comparing your scorecards with your partner. Here’s some of my favorite articles from the SelfDecode Personalized Genetics Blog that you should check out:

NOS3 Genes

Can This Gene Benefit Your Athletic Performance?

When you have the genetic variants for NOS3 that I do, it means that your athletic performance can suffer due to the gene’s effect on heart rate and energy balance. However, if improving your athletic performance is important to you, there are some specific supplements you can take to get the most out of your workout.


How to Tell if You’re Lectin Sensitive Using Your Genetic Data?

This scorecard isn’t a surprise to me, because I’ve known for years that I’m sensitive to lectins and have to follow a strict lectin-free diet. However, this post reminded me of a lifestyle habit that I need to incorporate to help optimize my CNR1 gene and help reduce my lectin sensitivity.

Beat “Brain Fog” With The Cannabinoid System

Brain fog is one of my favorite topics because when I learned how to fix my brain fog issues, my life completely changed. I went from a broke college drop out to a successful owner of 4 companies. One of the suggestions from this article to improve my CNR1 gene has actually been one of the key factors in helping me completely get rid of brain fog.

The Link Between Cannabinoid System & Weight Gain

Even though my CNR1 genetic variants are not good when it comes to brain fog or lectin sensitivity, they are great for keeping my weight under control! This gene plays a crucial role in the cannabinoid system and since my cannabinoid system is underactive, this actually helps to decrease appetite and slow my metabolism. Check your CNR1 and learn how to control your weight!


Can This Gene Help You Live Longer?

Researchers have found that people who live over 100 have something in common: they tend to have a specific variant of the PON1 gene. Unfortunately, my PON1 gene doesn’t set me up for a long life, but this article told me about some specific fruits I can eat to increase PON1 expression and expand my lifespan.

The Gene That Protects Your Heart

Heart disease is one of the leading causes of death in the world. Fortunately, PON1 protects your heart by clearing away fats in your blood. Unfortunately, genetic variants like mine can impact how well PON1 works. I plan to live a long life and that’s why I’ve incorporated all of the foods suggested in this article to help protect my heart and significantly boost my PON1 activity.

Is This Detox Gene Protecting You From Pesticides?

This article is interesting to me because even though I knew pesticides are bad, I didn’t realize that they are specifically worse for ME because of my genes! Check your PON1 gene to find out if pesticides are more dangerous for you than the average person.

No matter how long I study my own genes, it’s always entertaining to compare them with someone in my life. It’s interesting to see how the same gene can affect you and your partner so differently! Date night went from dinner and a movie to dinner and comparing genetic risk.

If you can’t explore your partner physically, now is a good time to explore what makes them who they are – and what better way to do that than exploring their DNA.

It’s always easier to make a change alongside someone else, so share these articles and get motivated to be your best self together!

About the Author

Joe Cohen, BS

Joe Cohen, BS

Joe Cohen flipped the script on conventional and alternative medicine…and it worked. Growing up, he suffered from inflammation, brain fog, fatigue, digestive problems, insomnia, anxiety, and other issues that were poorly understood in traditional healthcare. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. Based on his own health success, he went on to found SelfDecode, the world’s first direct-to-consumer DNA analyzer & precision health tool that utilizes AI-driven polygenic risk scoring to produce accurate insights and health recommendations. Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs.
Joe is a thriving entrepreneur, with a mission of empowering people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time.


1 Star2 Stars3 Stars4 Stars5 Stars
(1 votes, average: 1.00 out of 5)

FDA Compliance

The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.

Leave a Reply

Your email address will not be published. Required fields are marked *

Related Articles View All