Q & A – Stress & Headaches

Written by Joe Cohen, BS | Last updated:

We’ve had a lot of great questions coming in during our live VIP webinars lately, so I figured I’d share some of the questions and answers with you all. 

Question: When I have stress or anxiety, I get a headache within minutes. Are there specific genes I should be looking at for this issue?

YES! We actually have an entire DNA report dedicated to looking at all the genes related to headaches and migraines, but there are some specific genes that relate to both stress and headaches. 

One gene you’ll definitely want to look at is the MEF2D gene. The MEF2D is one of the genes that are activated when you get stressed, particularly if you have specific genetic variants. However, it’s also been linked to migraines. 

That’s because it can make the neurons in your brain fire faster and studies are showing that highly active neurons could be to blame for painful migraines. 

Basically, stress = increased MEF2D gene activity = excited neurons in the brain = headaches. 

So, if you’ve got the MEF2D genetic variants that are more prone to increased activity when you get stressed, it can definitely explain why stress leads to instant headaches. 

You can actually see your results for your MEF2D gene in this blog post and find a couple specific techniques on how to decrease MEF2D activity if it turns out that you do have the negative genotype.

If you want to submit your own questions for me to answer during our live VIP webinars, you can sign up for SelfDecode today

Besides all the awesome DNA health reports and personalized health suggestions that come with the subscription, you’ll also get to attend our live monthly webinar and submit your own questions to be answered. 

About the Author

Joe Cohen, BS

Joe Cohen, BS

Joe Cohen flipped the script on conventional and alternative medicine…and it worked. Growing up, he suffered from inflammation, brain fog, fatigue, digestive problems, insomnia, anxiety, and other issues that were poorly understood in traditional healthcare. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. Based on his own health success, he went on to found SelfDecode, the world’s first direct-to-consumer DNA analyzer & precision health tool that utilizes AI-driven polygenic risk scoring to produce accurate insights and health recommendations. Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs.
Joe is a thriving entrepreneur, with a mission of empowering people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time.


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