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This one supplement is proven to outperform Ozempic

Written by Joe Cohen, BS | Last updated:

What if I told you that there’s a supplement that has a similar mechanism as Ozempic, but actually outperforms it?

This is not hyperbole or clickbait. Keep reading, as the evidence is below.

In addition, it has no side effects (according to studies and my own experience) and is one of the healthiest things you can do.

It’s a supplement that I’ve been championing for over 12 years, and one that I never miss a day of.

You can call it the “natural ozempic” although I think that diminishes the plethora of additional benefits that it has.

This supplement is Resistant Starch.

Here’s how you can use Resistant Starch to improve your gut health, blood sugar, heart health, metabolism, cognitive function… oh and to help you reach a healthy weight.

But First, How Does Ozempic Work?

Ozempic promotes weight loss by mimicking GLP-1, which is a hormone naturally produced in the intestines in response to food intake.

Ozempic acts like GLP-1 in the body, binding to and activating GLP-1 receptors which helps regulate appetite and digestion.

When you take Ozempic, it tells your brain you’re full, so you eat less. It also slows down how fast your stomach empties, which means you feel full for longer after eating.

Resistant Starch does the same, and so much more.

Butyrate, GLP-1, and Resistant Starch

The types of fiber that increase GLP-1 the most are fermentable, or prebiotic fibers, specifically resistant starch.

These fibers reach the colon mostly intact, where they are fermented by beneficial gut microbes, leading to an increase in production of GLP-1, the hormone that Ozempic mimics.

In fact, resistant starch is far superior because it stimulates GLP-1 continually, whereas Ozempic is a GLP-1 activator – short-term boost.

A recent study showed that people who supplemented with resistant starch for 8 weeks lost an average of 6.2lbs (2.81kg) and improved insulin resistance.  [1]

This outperformed Ozempic, which took 13 weeks to get similar results [2].

The study used the same exact type of starch in Jo’s Resistant Starch, not the horrible potato starch or green banana starch that you will usually find.

As opposed to Ozempic, which also causes muscle loss, Resistant Starch (via butyrate) increases muscle growth [3].

It’s not a coincidence that I have a lot of muscle and little fat – while never being hungry, and rarely going to the gym. My main exercise comes from acro yoga.

People go on yoyo diets and lose a few pounds while feeling hungry all the time.

The real trick is to reach your goals and not be hungry!

It’s almost unheard of that with one natural intervention, someone can lose 6.2 pounds in 8 weeks!

I’ve been doing this for 14 years!

The funny thing is I don’t even take it for weight reasons.

There are so many other benefits to it.

Resistant starch increases butyrate the most among all dietary fibers, which is extremely important not just for fat reduction, but cognitive and gut function as well.

The amount of butyrate that resistant starch creates far outweighs how much butyrate supplements you can take before feeling nauseous.

Cognitive Function and Butyrate

Butyrate promotes the production of brain-derived neurotrophic factor (BDNF), a protein that supports the growth and maintenance of neurons.

By enhancing neuronal growth and plasticity, butyrate improves your learning and memory.

Additionally, butyrate has anti-inflammatory properties that can help protect against neurodegenerative diseases and cognitive decline associated with aging.

If I wrote about all the different things resistant starch helps with, this email would be a novel.

While Resistant Starch is one of those things that I recommend everyone take, I also recommend everyone look at SelfDecode before they take any supplement, to see how it helps them personally.

The SelfDecode AI recommendation engine looks at symptoms, conditions, goals, genetic risks, labs and lifestyle factors when prioritizing a recommendation.

For me Resistant Starch comes up at 55, which is actually quite high. It comes up 15 when filtered by supplements. It would be even higher if my goals were related to weight.

Why Lectin-Free Resistant Starch Is Best

All resistant starches you’ll find online that are from raw potatoes or green bananas are loaded with harmful lectins, which can contribute to food sensitivities and gut health issues – pretty much negating many of the health benefits that resistant starch and butyrate provide.

When I tried potato and green banana starch, it made me super bloated and brain foggy for days.

I had a hard time finding lectin-free Resistant Starch, so I created my own – Jo’s Resistant Starch, and it’s the only resistant starch I use.

When I was extremely sensitive to lectins, it was the only food besides beef and chicken that I had no reaction to.

Jo’s Resistant Starch is sourced in the USA and is lectin free, certified GMO Free, Kosher and Halal. It is tested for mold, yeasts and bacteria.

I use 40g/day in shakes, but it can also be used in baking as a substitute for flour.

My resistant starch is available on Amazon in the U.S. or on our website getjo.co.



About the Author

Joe Cohen, BS

Joe Cohen, BS

Joe Cohen flipped the script on conventional and alternative medicine…and it worked. Growing up, he suffered from inflammation, brain fog, fatigue, digestive problems, insomnia, anxiety, and other issues that were poorly understood in traditional healthcare. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. Based on his own health success, he went on to found SelfDecode, the world’s first direct-to-consumer DNA analyzer & precision health tool that utilizes AI-driven polygenic risk scoring to produce accurate insights and health recommendations. Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs.
Joe is a thriving entrepreneur, with a mission of empowering people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time.


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