Evidence Based This post has 7 references
4 /5

I Ate Fish For Two Weeks & Started to Lose My Memory

Written by Joe Cohen, BS | Last updated:

This post is written by Joe Cohen and is based solely on his opinion. All opinions expressed by authors and quoted sources are their own and do not necessarily reflect the opinions of the editors, publishers or editorial boards of SelfHacked. 

Some time ago I shared a health hack with my friend, Dr Mercola, and now whenever we meet he tells me how much he loves this health hack and uses it all the time now.

You see, a few years ago, after I had fixed all of my health issues, I started to experience serious memory problems and some brain fog. If I was older, I would’ve thought that I was coming down with dementia. The brain fog was different than what I’d get after eating grains or other foods I was sensitive to.

It was clear that this was not a food sensitivity. So what else could it be?

I took an inventory of my diet and lifestyle, and I realized that I was eating fish every day for 2 weeks.

Perhaps I was consuming some toxin in fish.

Knowing that fish are contaminated with heavy metals, I started taking a few supplements to detox mercury (NAC, lipoic acid, glutathione, etc.), but I didn’t notice any changes in my brain function.

Then I thought if it’s not heavy metals, then what is it? I knew fish had a lot of dioxins, PCBs, and toxins from plastics in the ocean.

Dioxins and PCBs are accumulate in fat tissue in the body and are both neurotoxic and carcinogenic. They have a range of negative health effects, including reducing thyroid hormones (T3) [1, 2].

A 2010 study found that children with highest concentrations of PBDE levels in their umbilical cord blood at birth had a significantly lower IQ (5.5 to 8.0 points), after correcting for sex, ethnicity, tobacco smoke exposure, and mother’s IQ [3].

According to one study, seafood eaters ingest up to 11,000 tiny pieces of plastic every year, and this number is growing [4].

These toxins from plastics bind very well to activated charcoal. I had tried activated charcoal before and didn’t notice any benefits from it.

But I figured that maybe it only helps when you’re intoxicated. So I tried 5g of activated charcoal in the form of a powder (equivalent to 20 pills).

My memory improved and my brain fog cleared in around 60-90 minutes!

Activated charcoal is charcoal with a chemically increased surface area which increases its ability to bind to or adsorb other chemicals. This reaction and absorption capacity is what makes activated charcoal great for detoxing!

Turns Out, I Don’t Detox Plastics Well

I looked on SelfDecode to see how I handle toxins, and I realized that I had certain ‘bad’ gene variants that prevented me from detoxing. An easy way to check for these genes is to check out our detox section on the SelfDecode blog. Here are my results, for example:

Low and behold, it turns out I have a genetic variant that was flagged by SelfDecode that showed I had problems detoxing plastics. I have the variant called UGT1A1*28.

According to SelfDecode:

UGT1A1 is one of the primary genes responsible for reduced detox ability.

According to some reports, the variant UGT1A1*28 causes a 70% reduction in enzyme activity [5].

UGT1A1 rs34983651 (found in 23andme V4)

  • ‘D’ (short for deletion, represents an absence of the extra ‘TA’) = Normal detox function
  • ‘I’ or ‘TA’ insertion = UGT1A1*28 = Increases your risk for toxicity

As you can see, with the ‘II’ genotype, I am at the highest risk for having toxicity issues.

Here are some snippets from the post:

  • A buildup of BPA in the body is linked to several disorders, including cancer, heart disease, and thyroid dysfunction. Removal of BPA is primarily the responsibility of UGT; genetic variations in UGT1A1 can lower the body’s ability to detox BPA-based plastics [6].
  • A small study of 15 people found that those with UGT1A1*28 remove BPAs in the breast tissue 10 times more slowly compared to those without the allele. This finding has important clinical implications: BPA exposure has been connected to breast cancer in several studies [6].

There are also other SNPs in this gene that increases the likelihood for toxicity to plastics, so you want to check those out as well.

While it’s more subtle, I still notice that when I eat seafood, my thinking gets a bit less clear. However, when I consume fish with activated charcoal, I don’t notice any negative effects from fish.

I will also consume activated charcoal when eating out, because I find that when I eat meat from restaurants, it often causes some gut problems, which is prevented by the charcoal. The same thing doesn’t happen with home-cooked meat.

So now I always make sure to consume activated charcoal whenever I eat seafood or eat out.

Activated charcoal has other health benefits as well that I like, such as lowering LDL cholesterol, which is still my only lab that is not optimal.

Additionally, I stopped drinking from plastic bottles once I found out this critical information. Plastics are a problem for everyone (see this interview), but it’s clear that I have even more of a problem with it than most people.

Plastics in the Ocean

Plastics in the ocean is a serious problem. Here are some facts about plastics in our oceans [7]:

  1. Every minute, one garbage truck of plastic is dumped into our oceans
  2. The cumulative amount of plastic in the ocean is set to increase tenfold by 2020 (from 2016).
  3. By 2050 there will be more plastic in the oceans than there are fish (by weight)
  4. Plastic is found in the ocean as far as 11km deep, meaning synthetic fibers have contaminated even the most remote places on Earth
  5. About 8 million metric tons of plastic are thrown into the ocean annually
  6. There are five massive patches of plastic in the oceans around the world. These huge concentrations of plastic debris cover large swaths of the ocean; the one between California and Hawaii is the size of the state of Texas

Advanced ‘Detox’ Hacks

If I really want to detox, I implement my advanced detox hack.

I use activated charcoal before I go into the sauna, and combine it with red light therapy.

The activated charcoal, sweating from the sauna and red light all synergize to create the best detoxification health hack out there.

If you decide to try this out for yourself, let me know what you think! Just tag me @mrbiohacker on Instagram.

About the Author

Joe Cohen, BS

Joe Cohen, BS

Joe Cohen flipped the script on conventional and alternative medicine…and it worked. Growing up, he suffered from inflammation, brain fog, fatigue, digestive problems, insomnia, anxiety, and other issues that were poorly understood in traditional healthcare. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. Based on his own health success, he went on to found SelfDecode, the world’s first direct-to-consumer DNA analyzer & precision health tool that utilizes AI-driven polygenic risk scoring to produce accurate insights and health recommendations. Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs.
Joe is a thriving entrepreneur, with a mission of empowering people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time.


1 Star2 Stars3 Stars4 Stars5 Stars
(8 votes, average: 4.00 out of 5)

FDA Compliance

The information on this website has not been evaluated by the Food & Drug Administration or any other medical body. We do not aim to diagnose, treat, cure or prevent any illness or disease. Information is shared for educational purposes only. You must consult your doctor before acting on any content on this website, especially if you are pregnant, nursing, taking medication, or have a medical condition.

Leave a Reply

Your email address will not be published. Required fields are marked *

Related Articles View All