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Joe Cohen Beat’s Bryan Johnson’s Blueprint Using Precision Health

Written by Joe Cohen, BS | Last updated:

Who is Bryan Johnson?

Bryan Johnson is the entrepreneur behind Venmo who spends 2 million dollars a year on his health to slow his aging. I spend 20k dollars a year on my health, with better results.

He has thrown down a challenge that whoever has better results than him should show them and what they do. So that is what I’m doing.

I did not start out healthier than Bryan, and in fact I was significantly less healthy. At a certain point, I was physically disabled and couldn’t work or go to school. My personalized regimen allowed me to completely fix these 60 health problems.

My Thoughts on Bryan Johnson

On a personal level, I have spoke with Bryan once and I quite like him. We are both competitive and I like that he has thrown down a challenge.

I also love that he takes a data driven approach and isn’t dogmatic. He says here’s what I’m doing, and here’s my results.

I wish we had more people like Bryan who are tinkering, testing and sharing so that we can see what a given individual does and what their results are.

Instead, most gurus go around talking about their beliefs and talk about how great they feel, but don’t talk about what their data says.

So, overall, I’m a big fan of the data approach. However, I believe the Bryan’s Blueprint protocol breaks down by implicitly assuming that the blueprint would work for other people. I believe people need their own customized blueprint’s.

Joe vs Bryan Johnson

See raw footage: Taking off shirt in conference

LOS ANGELES, CALIFORNIA – September 13, 2023: Bryan Johnson, tech entrepreneur and Founder of Blueprint, poses for a portrait at his home. Johnson follows a strict diet and lifestyle routine in an attempt to reduce his biological age. CREDIT: Philip Cheung for TIME

I typically measure around 300 different biomarkers on a consistent basis: Measuring My Health: Lab Tests & Data Points I Track

I’m willing to compare any of my results to Bryan’s.

Differences Between Joe & Bryan’s Regimen

Joe Bryan
Joe: Uses SelfDecode & believes in a personalized protocol Bryan: Believes his Blueprint is broadly applicable
Joe: Spends 20k USD/yr Bryan: Spends 2M USD/yr
Joe: Believes that people should try one thing at a time Bryan: Advocates for people to follow his Blueprint
Joe: No rigorous routine – listens to body  Bryan: Operates via a decision algorithm
Joe: Prioritizes living for the now and healthspan  Bryan: Prioritizes Lifespan (motto: Don’t Die)
Joe: Eats about 35 pounds of veggies a month  Bryan: 70 pounds of veggies a month
Joe: Doesn’t intermittent fast  Bryan: Fasts for 18hrs per day
Joe: Goes to sleep after 1AM (as a result of social life), a different time every night  Bryan: Goes to bed the same time every night (8PM)
Joe: Unrestricted eating – eats when hungry  Bryan: 10% Calorie Restriction, hungry all the time
Joe: Rx use: Repatha, Ezetimibe, Bempedoic acid (2x/wk)  Bryan: Rx: Rapamycin, Testosterone, Statin, Metformin, Acarbose, 17α-E, Levothyroxine + Armour Thyroid, Taladafil (Cialis), Phenylbutyric acid,
Joe: Meat-based diet  Bryan: Vegan diet
Joe: Higher protein, Medium fat, Lower carb (I typically consume around 140g+ of protein, less than 150g of carbs)  Bryan: Higher fat, Medium Protein, Medium Carb (Bryan consumes 107g protein a day, 185g carbs/day)
Joe: Not consistent diet – my only goal is to get >1.5g protein/kg/day – or 120g  Bryan: Same diet every day
Joe: Consumes high salt diet  Bryan: Consumes low salt diet
Joe: Limits eating 3-4 hours before bed  Bryan: Doesn’t eat for 8 hrs before bed
Joe: Tries to get 1hr of sun/day without sunscreen Bryan: Avoids the sun
Joe: AcroYoga, some walking and biking Bryan: 1 hr regimented workout routine
Joe: Natural body Bryan: Did genetic engineering to increase muscle mass, takes exogenous testosterone
Joe: Eats some unhealthy foods sometimes Bryan: Never eats junk foods
Joe: Low on Chocolate & Olive oil Bryan: Higher olive oil and chocolate

See Joe Cohen’s Regimen

About the Author

Joe Cohen, BS

Joe Cohen, BS

Joe Cohen flipped the script on conventional and alternative medicine…and it worked. Growing up, he suffered from inflammation, brain fog, fatigue, digestive problems, insomnia, anxiety, and other issues that were poorly understood in traditional healthcare. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. Based on his own health success, he went on to found SelfDecode, the world’s first direct-to-consumer DNA analyzer & precision health tool that utilizes AI-driven polygenic risk scoring to produce accurate insights and health recommendations. Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs.
Joe is a thriving entrepreneur, with a mission of empowering people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time.


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