Anxiety, Physical Pain & HTR2A; The Serotonin Gene

Written by Joe Cohen, BS | Last updated:

During our February 2021 live webinar about how to deal with anxiety, someone wrote in a very interesting question.

They asked about the connection between anxiety and physical pain.

Interestingly enough, it is quite common for someone to experience anxiety and physical pain together.

But, did you also know that the root cause of your anxiety and pain issues could also be contributing to a lackluster dating life?

How? Through serotonin genes, like HTR2A.

Variations in the HTR2A gene can result in lower serotonin and decreased brain growth factor (BDNF), both of which can make you less happy and more anxious.

Low serotonin levels have also been associated with chronic pain. And when it comes to dating, studies showed that low serotonin was particularly bad for men, making them seem less attractive and less popular.

Personally, I ended up with the semi-bad genetic variants for this gene:

I only got one of the bad alleles, which means I am at somewhat more risk and may still need to address this gene, especially if I have the symptoms…which I did (before I addressed them!).

Anxious, in pain and single

Sounds like really bad luck, doesn’t it?

What if I told you that you could turn that luck around by learning how to increase your serotonin levels?

Well, you can. Because that’s exactly what I did.

Once I learned which genes were contributing to my low serotonin levels, I was able to implement targeted recommendations, like taking specific supplements or starting new habits, that actually changed how my genes were functioning.

You might be stuck with the genes you have, but you aren’t stuck with the way they are working. You can actually overcome the negative effects with specific changes.

Increase Your Serotonin with Gene-Based Recommendations

You can check your own HTR2A gene when you sign up for SelfDecode today. You’ll get to see your own list of personalized recommendations to help ensure your serotonin gene is functioning optimally.

Plus, you can download your Anxiety, Mood and Pain DNA Reports to see the results for ALL of your genes related to these issues. HTR2A is just one of them. There are dozens.

About the Author

Joe Cohen, BS

Joe Cohen, BS

Joe Cohen flipped the script on conventional and alternative medicine…and it worked. Growing up, he suffered from inflammation, brain fog, fatigue, digestive problems, insomnia, anxiety, and other issues that were poorly understood in traditional healthcare. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. Based on his own health success, he went on to found SelfDecode, the world’s first direct-to-consumer DNA analyzer & precision health tool that utilizes AI-driven polygenic risk scoring to produce accurate insights and health recommendations. Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs.
Joe is a thriving entrepreneur, with a mission of empowering people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time.


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