Saffron, Focus and Sleep

Written by Joe Cohen, BS | Last updated:

I found a supplement that helped me focus on tasks more than anything else I’ve ever taken, including caffeine.

It’s even better than caffeine because it gave me no jittery or wired feeling.

And, on top of that, it also helped me sleep better.

I felt like I had the power to sleep whenever I wanted to because it put me in a meditative like state.

This game-changing supplement is Saffron.

The reason it got on my radar was because, after I recently updated all of my labs, symptoms, and goals into SelfDecode, it came up really high on my list of recommendations.

Here’s why Saffron is now considered a game-changer in my regimen.

Saffron and Focus

One of my main issues with focus was that I wasn’t really able to turn it off as easily as I’d like.

When I’d start focusing, it felt like I would tunnel vision and I’d be fixated on this one task, which is good in a sense but it can also be problematic, especially when it’s closer to bed time.

Your brain is still really active and it’s harder for you to wind down.

I also wanted to be able to have this strong focus but easily switch between tasks and then turn off my brain when it was time to rest and unwind.

Saffron helped put me in a more “relaxed focus.”

It does this by decreasing your glutamate levels.

High levels of glutamate cause you to be hyperactive and can also potentially make you unfocused.

And since I’ve been doing some experiments that had the side effect of increased glutamate, Saffron was even more effective than before.

It also helps counteract some of my negative genetic predispositions – specifically my DRD2 gene.

The DRD2 gene helps make dopamine D2 receptors. Those are proteins on the surface of brain cells that bind dopamine.

Dopamine is a neurotransmitter, a chemical messenger in the brain, that plays a crucial role in various cognitive functions, including attention.

Saffron helps balance dopamine levels in the brain, which enhances focus and concentration by facilitating communication between different regions of the brain involved in attentional processes.

So how can it do all this and also help with sleep?

Saffron, Sleep & Mood

This “relaxed focus” state that Saffron allows me to get into due to the decrease in glutamate and balance of dopamine helps put me in a meditative-like state.

If you’ve ever meditated, it gives you the exact feeling you get after a good bout of meditation.

You can say that this state helps me “focus” on unwinding and improving my sleep onset.

Saffron also increases your serotonin. Although, if you’re low on serotonin I believe that Saffron isn’t really the right supplement as it has a minor effect on it compared to other supplements like 5-HTP.

But if your serotonin levels are already normal or optimal, Saffron helps take it to the next level.

And the positive is that it doesn’t make you drowsy when you take it.

It essentially primes your brain to do whatever you want it to do.

Sounds magical right?

Is Saffron Your Top Recommendation?

If you’ve been following me for a while, you’ll know that I preach personalization.

I always leave a little asterisk when I talk about my game-changing supplements, because these are all based on my genes, labs, symptoms, and goals.

So, consider this sentence an asterisk to the whole email.

Saffron is definitely a new top supplement for me, but the truth is it might not be for you.

Your genetics are different than mine.

So is your lifestyle, which in return affects your labs in different ways.

You have different goals than me.

These all play a huge role in determining what supplements should top your list.

Which is why our SelfDecode technology analyzes all of these data points to give you your very own personalized diet, lifestyle, and supplement recommendations.

Are you ready to discover what your game-changing supplements are?



About the Author

Joe Cohen, BS

Joe Cohen, BS

Joe Cohen flipped the script on conventional and alternative medicine…and it worked. Growing up, he suffered from inflammation, brain fog, fatigue, digestive problems, insomnia, anxiety, and other issues that were poorly understood in traditional healthcare. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. Based on his own health success, he went on to found SelfDecode, the world’s first direct-to-consumer DNA analyzer & precision health tool that utilizes AI-driven polygenic risk scoring to produce accurate insights and health recommendations. Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs.
Joe is a thriving entrepreneur, with a mission of empowering people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time.


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