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SLC6A4 Stress Gene, Fatigue, and Hidden Inflammation

Written by Joe Cohen, BS | Last updated:
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Did you know stress may not come from your environment, job, or lifestyle?

There’s actually a single gene responsible for transporting serotonin in your brain. This gene influences how happy you feel and how stressed you are. So if you often feel stressed or “down,” it’s likely because of this gene.

The SLC6A4 Gene

If you have low-activity variants of SLC6A4, you are more sensitive to stress. This is because the SLC6A4 gene encodes a serotonin transporter protein. So a low-activity variant SLC6A4 may be the hidden culprit of your stress!

When you’re stressed, cortisol floods your bloodstream. Cortisol then decreases serotonin signaling. This endless cycle is why so many people feel stressed all day.

The lockdowns, working from home, and health crises make the stress even worse…

SLC6A4 And Stress = Fatigue

If stress persists, you’ll feel more tired. Stress and fatigue are so closely related, they often arise together. Research even shows that stress can sometimes lead to Chronic Fatigue Syndrome (CFS).

If you ever feel stressed and worn out, it doesn’t always have to do with your diet, exercise, or sleep. A low-activity variant SLC6A4 gene contributes heavily to stress… And in turn, may cause you to feel tired, foggy, and worn down.

But there is good news! Understanding your genes helps you combat persistent stress and fatigue.

You can alter your lifestyle to offset a low-activity variant SLC6A4 gene.

SelfDecode To Eliminate Stress & Fatigue…

When I feel stressed, I refer back to my personalized genetics blogs and target the problem. And when I notice my energy running out, I read through the 24 custom SelfDecode Wellness Reports to make some changes.

Eliminating stress and fatigue only works if you understand your own genes. Specifically, you must know more about your SLC6A4 gene to enhance the way you feel.

Without a clear analysis of SLC6A4 – and other stress-related genes – your serotonin can’t give you the boost you need.

Here’s how SelfDecode reduces stress and fatigue…

The only reason I’m able to feel energetic and calm running 4 companies is because of SelfDecode’s technology. Adjusting my entire lifestyle based on the personalized wellness reports allows me to live free from any health issues.

Now, you can do the same with your own personalized Anxiety DNA Report.

Imagine feeling energized all day long and having extra time for the activities you love. Imagine feeling all that stress disappear with a few simple changes…

Our SelfDecode DNA Analysis makes this process really simple.

But please do not wait for a fleeting spark of motivation to do this. If you hold off until “tomorrow, when I have more free time”… It’s only another day of hidden health issues popping up.

That’s why you get ALL of this when you click the button below today:

  • In-Depth SLC6A4 Stress & Fatigue Analysis – use SelfDecode reports to understand your SLC6A4 gene to eliminate stress and fatigue for good.
  • 400+ SelfDecode Personalized Genetics Blogs – 400 personalized genetics articles help you get to the root cause of your health issues using your unique DNA.
  • 24 Personalized DNA Wellness Reports – in-depth genetic reports on topics like anxiety, cognitive function, mood, and sleep that provide you with recommendations specific for your body, so that you can solve any health problem you’re experiencing.
  • 1500+ SelfHacked articles (ad-free!) – Read from over 1500 science-based health articles that go in-depth on the benefits of natural supplements and lifestyle health.
  • Lab Test Analyzer tool – Upload your lab results and discover how you can get your levels to the optimal range. We analyze ~1000 labs. We will add any lab that we don’t have!
  • SelfDecode Personalized Genetics Blog – 400 personalized genetics articles help you get to the root cause of your health issues using your unique DNA.
  • Personalized DNA Wellness Reports – in-depth genetic reports on topics like cognitive function, mood, and sleep that provide you with recommendations specific for your body, so that you can solve any health problem you’re experiencing.
  • ALL SelfHacked articles (ad-free!) – Read from over 1500 science-based health articles that go in-depth on the benefits of natural supplement and lifestyle health changes.
  • Lab Test Analyzer tool – Upload your lab results and discover how you can get your levels to the optimal range. We analyze ~1000 labs. We will add any lab that we don’t have!
  • And so much more!

About the Author

Joe Cohen, BS

Joe Cohen, BS

Joe Cohen flipped the script on conventional and alternative medicine…and it worked. Growing up, he suffered from inflammation, brain fog, fatigue, digestive problems, insomnia, anxiety, and other issues that were poorly understood in traditional healthcare. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. Based on his own health success, he went on to found SelfDecode, the world’s first direct-to-consumer DNA analyzer & precision health tool that utilizes AI-driven polygenic risk scoring to produce accurate insights and health recommendations. Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs.
Joe is a thriving entrepreneur, with a mission of empowering people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time.

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