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Vitamin E, TNFAIP3 Gene, and Joint Inflammation

Written by Joe Cohen, BS | Last updated:
The osteocalcin test can point to bone problems HLA-B27

If you hear someone talk about joint pain – like rheumatoid arthritis – you probably think of the elderly, right?

Unfortunately, this is a common myth that gives many people a false sense of security.

The truth is anyone can get joint inflammation at any age. It’s not just for when you get older, and the cause of joint pain isn’t just from wear and tear and old age.

Joint inflammation occurs when your immune cells accidentally mislabel your own tissues as invading pathogens and start attacking them. This can happen to anyone and can cause significant joint pain.

But let’s take a step back and assume it does only occur with the elderly. Would you just wait until you got older and pray you don’t get it?

No! The best thing you can do is take preventative measures for now and in the future.

One of the strongest contributing factors is coded into our DNA: many genes and variants have been associated with joint inflammation.

Luckily, with the revolutionary technology of a gene-based tool like SelfDecode, you can unlock the answers within your DNA.

I’m super excited to announce our Joint Inflammation DNA Report! This report will help anyone experiencing joint inflammation find the perfect diet, supplement, and lifestyle changes to naturally decrease inflammation and reduce your pain!

It also plays a key role in providing you with suggestions to take preventative actions to optimize your health so that you’ll never have to deal with it in the first place!

Vitamin E, TNFAIP3 Gene, and Joint Inflammation

Vitamin E is one of the key players in determining your risk of suffering from joint inflammation.

What’s the link with your DNA?

The TNFAIP3 gene helps reduce the activity of an inflammatory protein involved in the development of joint inflammation issues like rheumatoid arthritis.

The negative variant is underactive, so it doesn’t work as well as it should.

Vitamin E helps increase TNFAIP3 activity, so low Vitamin E levels means increased inflammation and an increased risk of developing joint inflammation issues.

If you have the good variant of the TNFAIP3 gene, low Vitamin E levels will still negatively affect your susceptibility. But if you carry the bad variant, it’s even worse!

This is a good example as to why understanding YOUR genes is the key to building a personalized regimen that will optimize your health and help you with your joint problems!

Get Started On Your Journey To Better Health

Once you’ve had your genes tested with our DNA kit (or upload a DNA file you already have), you’ll instantly get access to this report to start implementing better changes to your life.

The Joint Inflammation Report analyzes 41 genes that can affect your joints and, based on your genetic variants, will provide you with personalized diet, lifestyle, and supplement recommendations that will help YOU with your health issue!

Sign up today and you’ll also get access to:

  • Personalized blog articles with inflammation-reducing strategies based on your genes that’ll have you hopping out of bed pain-free!
  • DNA Wellness Reports that can help you solve many other health problems like Anxiety, Fatigue, Gut Health, and more!
  • The lab analyzer tool where you can analyze your labs related to inflammation (like Vitamin E) and get recommendations to bring your levels to optimal range.

About the Author

Joe Cohen, BS

Joe Cohen, BS

Joe Cohen flipped the script on conventional and alternative medicine…and it worked. Growing up, he suffered from inflammation, brain fog, fatigue, digestive problems, insomnia, anxiety, and other issues that were poorly understood in traditional healthcare. Frustrated by the lack of good information and tools, Joe decided to embark on a learning journey to decode his DNA and track his biomarkers in search of better health. Through this personalized approach, he discovered his genetic weaknesses and was able to optimize his health 10X better than he ever thought was possible. Based on his own health success, he went on to found SelfDecode, the world’s first direct-to-consumer DNA analyzer & precision health tool that utilizes AI-driven polygenic risk scoring to produce accurate insights and health recommendations. Today, SelfDecode has helped over 100,000 people understand how to get healthier using their DNA and labs.
Joe is a thriving entrepreneur, with a mission of empowering people to take advantage of the precision health revolution and uncover insights from their DNA and biomarkers so that we can all feel great all of the time.

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